| Date | Transaction | |||
| 7/31/08 | Sent OF Manny Ramirez to the Los Angeles Dodgers; Acquired OF Jason Bay from the Pittsburgh Pirates in exchange for RHP Craig Hansen and OF Brandon Moss. | |||
| 7/25/08 | Activated DH David Ortiz from the 15-day disabled list. | |||
| 7/24/08 | Optioned OF Brandon Moss to Triple-A Pawtucket. | |||
| 7/20/08 | Recalled RHP Justin Masterson from Triple-A Pawtucket; Placed RHP David Aardsma on the 15-day disabled list, retroactive to July 19, with a right groin strain. | |||
| 7/12/08 | Placed SS Julio Lugo on the 15-day disabled list with a torn left quadriceps muscle; Recalled INF Jed Lowrie from Triple-A Pawtucket. | |||
| 7/11/08 | Recalled RHP Clay Buchholz from Triple-A Pawtucket; Optioned 1B/OF Jeff Bailey to Triple-A Pawtucket. | |||
| 7/7/08 | Recalled 1B/OF Jeff Bailey from Triple-A Pawtucket; Optioned RHP Justin Masterson to Triple-A Pawtucket. | |||
| 7/3/08 | Activated RHP Mike Timlin from the 15-day disabled list. | |||
| 7/2/08 | Optioned RHP Chris Smith to Triple-A Pawtucket. | |||
