FORT MYERS, Fla. -- Anibal Sanchez, who was traded along with Hanley Ramirez to Florida for Josh Beckett back in 2005, fired three shutout innings in an 11-2 win over the Red Sox on Saturday afternoon at City of Palms Park.

Coming off a career-high 13 wins last year, the former Boston prospect was on his game in this one, allowing one hit, one walk, while striking out three. Sanchez was also efficient, throwing 43 pitches.

"I like that. Right now, I am looking for 15 pitches or less an inning," Sanchez said. "I don't want to throw too many balls and I don't want to go deep on the counts. Right now, I want to throw every batter a first-pitch strike."

Sanchez had plenty of offense at his back, as the Marlins scored three in the first, two in the second and two more in the third against Daisuke Matsuzaka.

Outfielder Dewayne Wise, trying to win a spot on Florida's bench, had a big day, going 3-for-4 with a homer, two runs and two RBIs.

"People around the league know I can play defense. I just think it's about getting an opportunity [to get at-bats]," Wise said. "I know I can do it."

Gabby Sanchez also swung the bat well, reaching base in all four plate appearances. Sanchez had two hits, two walks, two runs and two RBIs.

For Dice-K and the Red Sox, it was a tough afternoon. Matsuzaka allowed six hits and seven runs, five of which were earned. The righty walked two and struck out one, throwing 55 pitches in his second outing of the spring.

Veteran knuckleballer Tim Wakefield gave up five hits and two runs over 2 2/3 innings, walking two and striking out two.

Closer Jonathan Papelbon turned in a scoreless inning. Bobby Jenks, making his second Grapefruit League outing, was impressive, striking out two of the three batters he faced in the ninth.

"That's a really sharp breaking ball we saw today," said Red Sox manager Terry Francona. "His velocity is probably a little more than we expected early on in camp. That was a good inning."

Darnell McDonald, who made the start in right field on a day J.D. Drew had the flu, came up with two hits, including an RBI double.

Red Sox up next: With Jon Lester scratched due to the flu, right-hander Michael Bowden will start Sunday afternoon's game in Port St. Lucie against the Mets at 1:05 p.m. ET. Jed Lowrie, Lars Anderson and Ryan Kalish will be among the position players on the trip, and the game will air live on MLB.TV.

Marlins up next: The Marlins will face the Cardinals on Sunday at 1:05 p.m. Chris Volstad makes the start.