| Club Records -- Batting | Opponent | Date | |
|---|---|---|---|
| Most Runs, Inning -- 12 | Tampa Bay Devil Rays | 4/11/02 | |
| Most Runs -- 23 | Toronto Blue Jays | 9/28/00 | |
| Most Runs, Road Game -- 22 | Atlanta Braves | 6/13/99 | |
| Most Runs Yielded, Inning -- 16 | Texas Rangers | 4/19/96 | |
| Most Runs Yielded, Inning, Home -- 11 | Tampa Bay Devil Rays | 8/28/07 | |
| Most Runs Yielded, Home -- 30 | Texas Rangers | 8/22/07 | |
| Largest Win Margin -- 22 | Toronto Blue Jays | 9/22/00 | |
| Largest Win Margin, Shutout -- 17 | Chicago White Sox | 7/27/69 | |
| Largest Loss Margin -- 27 | Texas Rangers | 8/22/07 | |
| Largest Loss Margin, Shutout -- 16 | New York Yankees | 4/30/60 | |
| Most Hits, Inning -- 11 | Tampa Bay Devil Rays | 4/11/02 | |
| Most Hits Yielded, Inning - 11 | Detroit Tigers | 9/20/83 | |
| Most Hits -- 26 | California Angels | 8/28/80 | |
| Most Hits, Away Game -- 25 | Atlanta Braves | 6/13/99 | |
| Most Hits, Doubleheader -- 35 | Kansas City Royals | 6/23/91 | |
| Most Hits Yielded, Home Game -- 29 | Texas Rangers | 8/22/07 | |
| Most Doubles -- 9 | Minnesota Twins | 7/30/96 | |
| Most Triples -- 3 | Minnesota Twins | 4/29/93 | |
| Most Home Runs -- 7 | Boston Red Sox | 5/7/67 | |
| Most Total Bases -- 43 | Texas Rangers | 5/16/99 | |
| Most Total Bases, Opponent -- 53 | Toronto Blue Jays | 9/14/87 | |
| Most Extra Base Hits -- 12 | Detroit Tigers | 8/17/08 | |
| Most Extra Base Hits, Opponent -- 12 | Detroit Tigers | 6/21/87 | |
| Most Stolen Bases -- 7 | Oakland Athletics | 8/28/86 | |
| Most Stolen Bases, Opponent -- 8 | Kansas City Royals | 8/1/98 | |
| Most Left On Base -- 21 | Boston Red Sox | 8/25/68 | |
| Most Left On Base, 9 Innings -- 18 | Boston Red Sox | 5/15/71 | |
| Most Left On Base, Shutout Loss -- 15 | Seattle Mariners | 4/9/93 | |
| Most Strikeouts, Game, 9 Innings -- 17 | Seattle Mariners, Randy Johnson | 5/26/95 | |
| Most Strikeouts Game, Extra Innings -- 23 | Cleveland Indians | 10/5/96 | |
| Most Walks, Game -- 15 | Cleveland Indians | 9/28/73 | |
| Most GIDP, Game -- 6 | Kansas City Royals | 5/6/72 | |
| Individual Records -- Batting | Player(s) | Opponent | Date |
|---|---|---|---|
| Most Hits -- 6 | Cal Ripken | Atlanta Braves | 6/13/99 |
| Most Hits, Home Game -- 5 | 8 times; last: Miguel Tejada | Boston Red Sox | 7/9/05 |
| Most Runs -- 5 | Cal Ripken | Atlanta Braves | 6/13/99 |
| Most RBI -- 9 | Jim Gentile | Minnesota Twins | 5/9/61 |
| Most RBI, Home Game -- 7 | Boog Powell | Kansas City Athletics | 7/6/66 |
| Most RBI, at OPACY -- 6 | 5 times; last: Rafael Palmeiro | Boston Red Sox | 7/9/05 |
| Most RBI, Opponent -- 9 | Danny Tartabull | New York Yankees | 9/8/92 |
| Most RBI, Doubleheader -- 11 | Boog Powell | Kansas City Athletics | 7/6/66 |
| Most Doubles -- 4 | 4 times; last: Albert Belle | Oakland A's | 9/23/99 |
| Most Triples -- 3 | Al Bumbry | Milwaukee Brewers | 9/22/73 |
| Most Home Runs -- 3 | 18 times; last: Nick Markakis | Minnesota Twins | 8/22/06 |
| Most Total Bases -- 13 | Eddie Murray | Toronto Blue Jays | 9/14/80 |
| Most Total Bases, Home Game -- 13 | Roberto Alomar | Boston Red Sox | 4/26/97 |
| Most Total Bases, Opponent -- 16 | Rocky Colavito | Cleveland Indians | 6/10/59 |
| Most Stolen Bases -- 4 | 3 times; last: Brian Roberts | Chicago White Sox | 5/4/04 |
| Most Stolen Bases, Opponent - 5 | Kenny Lofton | Cleveland Indians | 9/3/00 |
| Most Bases On Balls -- 5 | Bobby Grich | Chicago White Sox | 8/9/75 |
| Most Strikeouts, 9 Inning Game -- 5 | Don Buford | Chicago White Sox | 8/26/71 |
| Most Strikeouts, Extra Inning Game -- 6 | Sam Horn | Kansas City Royals | 7/17/91 |
| Most Times Reaching Base on Error -- 3 | Phil Bradley | Texas Rangers | 8/4/89 |
| Most HBP, Game -- 3 | Melvin Mora | Toronto Blue Jays | 7/18/02 |
| Most HBP, One Inning -- 2 | Brady Anderson | Texas Rangers | 5/23/99 |
| Club Records -- Pitching | Opponent | Date | |
|---|---|---|---|
| Most Strikeouts, 9 inning game -- 17 | Boston Red Sox | 9/18/68 | |
| Most Strikeouts, extra inning game -- 21 (19 inn) | Washington Senators | 6/4/67 | |
| Most Base on Balls, game -- 18 (16 inn) | Philadelphia Orioles | 7/2/04 | |
| Individual Records -- Pitching | Player(s) | Opponent | Date |
|---|---|---|---|
| Most Strikeouts -- 15 | 8 times; last: Mike Mussina | Boston Red Sox | 9/24/00 |
| Most Base on Balls -- 12 | Jack Fisher | Los Angeles Angels | 8/30/61 |
| Most Innings Pitched -- 16 | Jerry Walker | Chicago White Sox | 9/11/59 |
| Fewest Batters Faced, 9 inning game -- 27 | 3 times; last: Bob Milacki | Minnesota Twins | 4/23/89 |
| Most Wild Pitches -- 4 | Daniel Cabrera | Washington Nationals | 6/25/06 |
| Most Consecutive Shutouts -- 3 | 5 times; last: Jim Palmer | 1978 | |
| Most Consecutive Games Won, Reliever -- 3 | Grant Jackson | 9/29,30 10/1/74 | |
| Most Wins, One Day -- 2 | Wes Stock | Cleveland Indians | 5/26/63 |
| Most Losses, One Day -- 2 | Don Aase | Oakland Athletics | 8/28/86 |